Cannabinoid of the Month: Tetrahydrocannabivarin (THCV) | AusCannaReviews
This month, we’re taking a deeper look at Tetrahydrocannabivarin (THCV), a non-psychoactive cannabinoid found in cannabis plants. THCV was first discovered in 1970 by Edward Gill and is gaining recognition in the medicinal cannabis community for its unique therapeutic properties.
THCV plays a significant role in the cannabis plant’s chemical composition. It is a homolog of THC, meaning it shares a similar molecular structure but with a few differences that lead to varied effects. THCV is typically found in higher concentrations in plants native to central Asia and southern Africa.
One of the most notable potential benefits of THCV is its ability to suppress appetite, which contrasts sharply with THC’s appetite-stimulating effects. A study published in the Journal of Cannabis Research in January 20202 found that THCV can reduce appetite and increase satiety, making it a potential treatment for obesity and related metabolic disorders. By modulating the CB1 and CB2 receptors differently than THC, THCV can help regulate food intake and support weight management.
While THC can exacerbate anxiety in some individuals, THCV has been observed to have anxiolytic effects without significant psychoactivity. A comparative study published in the Journal of Psychopharmacology in July 0f 2011 found that THCV can reduce anxiety-related (obsessive-compulsive) behaviours in animal models, suggesting its potential as a therapeutic agent for anxiety disorders. This makes THCV a promising alternative for patients seeking relief from anxiety without the risk of THC-induced paranoia or psychoactive effects.
THCV has shown potential in improving cognitive function, particularly in enhancing focus and mental clarity. Research indicates that THCV may act as a neuroprotective agent, which can be beneficial in managing neurodegenerative diseases like Parkinson’s disease. A study published in Brain Sciences in November 2021 highlighted THCV’s ability to improve motor control and reduce tremors, demonstrating its potential for improving cognitive and motor functions.
THCV represents a promising addition to the medicinal cannabis arsenal, offering potential benefits for appetite suppression, anxiety relief, and cognitive enhancement. As research continues to uncover more about this unique cannabinoid, it could play a significant role in future treatment strategies for various conditions.
If you’re looking for medicinal cultivars on the Australian market that are high in THCV**…
PureKann’s Kosher Kush Flower (Total THCV 0.4%)
FOMO’s Godfather’s Gift Flower (Total THCV 0.279%)
MJ POPs Kushy Flower (Total THCV 0.2%)
Cannatrek’s T22 Golden Bay Flower (Total THCV 0.115%)
Cannatrek’s T18 Jasper Flower (Total THCV 0.079%)
Grow Group’s SB 26 Waffle Bites Flower (Total THCV 0.05%)
**Information comes from COAs listed on Catalyst by honahlee.
This substack aims to provide anecdotal information from my personal experiences in hopes it will lead to meaningful conversations between my readers and their healthcare professionals about medicinal cannabis.
I have no formal training in medicine or science. This article does not constitute medical advice.